Dual time point FDG-PET/CT imaging… Potential tool for diagnosis of breast cancer

Dual time point FDG-PET/CT imaging… Potential tool for diagnosis of breast cancer
A.A. Zytoon, K. Murakami, M.R. El-Kholy, E. El-Shorbagy
Clinical Radiology (2008) 63, 1213e1227

Link to Journal

This is an interesting Egyptian study showing that dual time point FDG-PET/CT improves the discrimination between non-invasive and invasive cancers, and provided superior sensitivity for the detection of small cancers and cancers in dense breast.

PET/CT in breast cancer is becoming increasingly used in the western world, and new indications are regularly being found. This may be one of them if validated in another study

The mammographic correlations of a new immunohistochemical classification of invasive breast cancer

The mammographic correlations of a new immunohistochemical classification of invasive breast cancer
Clinical Radiology, 2008, 63; 11: 1228-1235

Link to Journal

The mammographic features of breast cancer show significant correlation with molecular classes of invasive breast cancer identified by protein expression IHC analysis. The biological reasons for the findings and implications of these regarding imaging protocols require further study and may provide mechanisms for improvement of detection of these lesions

Radiological appearances of papillary breast lesions

Radiological appearances of papillary breast lesions
M.J. Brookes and A.G. Bourke
Clinical Radiology 2008 63; 11:1265-1273

Link to Journal

The commonest mammographic appearance of a papillary tumour is as a soft-tissue mass, with calcification present in less than half of cases. When calcification is present the pattern is variable, but clusters of pleomorphic calcification can occur, sometimes resembling the mammographic appearance of invasive ductal carcinoma. Ultrasonography of papillary lesions typically shows a solid, oval, intraductal mass, often associated with duct dilatation. A cystic component is also commonly seen, and lesions may appear hypervascular on colour Doppler ultrasound. Magnetic resonance imaging (MRI) has a high sensitivity, but low specificity for detecting papillary tumours, and is useful in establishing the extent and distribution of lesions in patients with multiple papillomatosis. Despite a benign histology on core biopsy, an argument exists for complete surgical excision of all papillary tumours, as a significant proportion of papillomas will contain foci of atypia or overt malignant change

Dual time point FDG-PET/CT imaging… Potential tool for diagnosis of breast cancer

Dual time point FDG-PET/CT imaging… Potential tool for diagnosis of breast cancer
A.A. Zytoon, K. Murakami, M.R. El-Kholy and E. El-Shorbagy
Clinical Radiology 2008 63,11: 1213-1227

Link to Journal

Dual time point FDG-PET/CT improves the discrimination between non-invasive and invasive cancers, and provided superior sensitivity for the detection of small cancers and cancers in dense breast